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Tetrazzini Casserole

Modified: Jun 15, 2025 by Chantal Kirkland · This post may contain affiliate links · Leave a Comment

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Picture yourself on a chilly evening, wrapped in a cozy blanket, with the aroma of something delicious wafting through your home. That something is a steaming, golden-brown Tetrazzini Casserole fresh out of the oven.

closeup of a baking dish full of Tetrazzini Casserole

This dish brings together succulent turkey, earthy mushrooms, and a velvety sauce that tastes like a warm hug in every bite. Not only is it mouthwateringly good, but it's also a versatile recipe that you can adapt to suit your dietary needs.

Jump to:
  • Tetrazzini Casserole
  • 📖Printable Recipe:
  • Tetrazzini Casserole
  • 📋Ingredients
  • 🔪How Do I Make It?
  • 🍽What Do I Serve With This Casserole Dish?
  • ⏲️Chef's Tip
  • 💭Frequently Asked Questions
  • 🥘More Easy Casseroles

Tetrazzini Casserole

🎥Video Recipe:

📖Printable Recipe:

closeup of a baking dish full of Tetrazzini Casserole

Tetrazzini Casserole

Tetrazzini Casserole is more than just a meal; it's a comforting experience that brings people together.
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Print Recipe Pin Recipe
Prep Time 20 minutes mins
Cook Time 25 minutes mins
Course Main Course
Cuisine American
Servings 6
Calories 606 kcal

Ingredients
  

  • 300 g 10 oz cremini mushrooms, cut into quarters
  • 500 g 1 pound turkey breast, cut into pieces
  • 3 garlic cloves minced
  • 3 tablespoon butter
  • 300 g 10 oz spaghetti
  • 1 ¼ cup chicken stock
  • ⅓ cup white wine
  • 2 tablespoon all-purpose flour
  • ⅔ cup milk
  • ⅔ cup mozzarella shredded
  • ⅔ cup frozen peas
  • 1 teaspoon dry oregano
  • ½ cup panko breadcrumbs
  • ⅓ cup parmesan cheese
  • 3 tablespoon olive oil
  • ½ medium white onion chopped
  • ½ cup cream cheese

Instructions
 

  • Preheat the oven to 180C/350F.
  • In a large pan, heat up olive oil and brown turkey pieces on both sides, season with salt and pepper.
    3 tablespoon olive oil, 500 g 1 pound turkey breast, cut into pieces
    frying bacon to make a sauce for Tetrazzini Casserole
  • Remove turkey from the pan, add butter and saute onion for 3-4 minutes. Stir in mushrooms, cook for 10 minutes. Add oregano and garlic, cook for 30 seconds more.
    300 g 10 oz cremini mushrooms, cut into quarters, 3 garlic cloves, 3 tablespoon butter, ½ medium white onion, 1 teaspoon dry oregano
    sauteeing mushrooms to make a sauce for Tetrazzini Casserole
  • Mix everything with flour, cook for 30 seconds, then add wine and chicken stock. Pour in milk and mix in cream cheese, let it melt.
    1 ¼ cup chicken stock, ⅓ cup white wine, 2 tablespoon all-purpose flour, ⅔ cup milk, ½ cup cream cheese
    sauteeing mushrooms and thickener to make a sauce for Tetrazzini Casserole
  • Add turkey, peas and half-boiled spaghetti. Bring to a boil and transfer into a baking dish and top evenly with mozzarella.
    300 g 10 oz spaghetti, ⅔ cup frozen peas, ⅔ cup mozzarella
    adding green onion to sauce to mushroom sauce make Tetrazzini Casserole
  • In a small bowl combine breadcrumbs with olive oil and parmesan cheese.
    ½ cup panko breadcrumbs, 3 tablespoon olive oil, ⅓ cup parmesan cheese
    how to make breadcrumb topping for Tetrazzini Casserole
  • Sprinkle breadcrumbs on top evenly.
  • Bake for 25 minutes.
    spreading breadcrumbs over Tetrazzini Casserole prior to baking

Video

Nutrition

Calories: 606kcalCarbohydrates: 54gProtein: 36gFat: 28gSaturated Fat: 12gPolyunsaturated Fat: 2gMonounsaturated Fat: 11gTrans Fat: 0.2gCholesterol: 98mgSodium: 620mgPotassium: 742mgFiber: 3gSugar: 7gVitamin A: 1.046IUVitamin C: 3mgCalcium: 241mgIron: 3mg
Keyword casserole, Mozzarella, mushroom, spaghetti, Tetrazzini, Turkey
Tried this recipe?Let us know how it was!

📋Ingredients

  • 300 g (10 oz) cremini mushrooms, cut into quarters
  • 500 g (1 pound) turkey breast, cut into pieces
  • 3 garlic cloves, minced
  • 3 tablespoon butter
  • 300 g (10 oz) spaghetti
  • 1 ¼ cup chicken stock
  • ⅓ cup white wine
  • 2 tablespoon all-purpose flour
  • ⅔ cup milk
  • ⅔ cup mozzarella, shredded
  • ⅔ cup frozen peas
  • 1 teaspoon dry oregano
  • ½ cup panko breadcrumbs
  • ⅓ cup parmesan cheese
  • 3 tablespoon olive oil
  • ½ medium white onion, chopped
  • ½ cup cream cheese
ingredients laid out on a table to make Tetrazzini Casserole

🔪How Do I Make It?

Preheat the oven to 180C/350F.

In a large pan, heat up olive oil and brown turkey pieces on both sides, season with salt and pepper.

frying bacon to make a sauce for Tetrazzini Casserole

Remove turkey from the pan, add butter and saute onion for 3-4 minutes. Stir in mushrooms, cook for 10 minutes. Add oregano and garlic, cook for 30 seconds more. 

sauteeing mushrooms to make a sauce for Tetrazzini Casserole

Mix everything with flour, cook for 30 seconds, then add wine and chicken stock. Pour in milk and mix in cream cheese, let it melt.

sauteeing mushrooms and thickener to make a sauce for Tetrazzini Casserole

Add chicken, peas and half-boiled spaghetti. Bring to a boil and transfer into a baking dish and top evenly with mozzarella.

adding green onion to sauce to mushroom sauce make Tetrazzini Casserole

In a small bowl combine breadcrumbs with olive oil and parmesan cheese.

how to make breadcrumb topping for Tetrazzini Casserole

Sprinkle breadcrumbs on top evenly.

Bake for 25 minutes. 

spreading breadcrumbs over Tetrazzini Casserole prior to baking

🍽What Do I Serve With This Casserole Dish?

Fresh Green Salad

A fresh green salad pairs perfectly with Tetrazzini Casserole. The crispness of the greens and the tangy dressing offer a refreshing contrast to the rich and creamy casserole. Try mixing arugula, spinach, and kale with a simple vinaigrette made from olive oil, lemon juice, salt, and pepper. You can also add some cherry tomatoes and cucumber slices for extra crunch.

Garlic Bread

Garlic bread is another excellent side dish that complements the flavors of Tetrazzini Casserole. The buttery, garlicky bread is perfect for sopping up any extra sauce, and it adds a deliciously crunchy texture to your meal. To make garlic bread, simply slice a loaf of French bread, spread garlic butter on each slice, and bake until golden brown.

Steamed Vegetables

For those looking to keep things light, steamed vegetables are a wonderful option. Broccoli, carrots, and green beans are great choices. They add vibrant colors to your plate and provide a healthy, nutritious side dish. A sprinkle of sea salt and a squeeze of lemon juice can enhance their natural flavors without overpowering the casserole.

closeup of a baking dish of Tetrazzini Casserole

⏲️Chef's Tip

Choose Quality Ingredients

Quality ingredients can make a huge difference in the final outcome of your dish. Opt for free-range turkey breast, organic mushrooms, and high-quality stock. Fresh herbs can also elevate the flavors, so if possible, use fresh oregano instead of dried.

Cook the Pasta Al Dente

Cooking the pasta al dente is crucial for a perfect Tetrazzini Casserole. Since the pasta will continue to cook in the oven, boiling it until it's just firm to the bite will prevent it from becoming mushy. Aim for about half the usual cooking time for spaghetti.

Season Generously

Don't be shy with your seasonings. Salt and pepper should be added at various stages of cooking to ensure every layer of the dish is well-seasoned. Additionally, tasting as you go can help you adjust the flavors to your liking.

baking dish of Tetrazzini Casserole on a table with extra ingredients

💭Frequently Asked Questions

Can I Make This Dish Ahead of Time?

Yes, Tetrazzini Casserole is a perfect make-ahead dish. You can prepare it up to the point of baking and store it covered in the refrigerator for up to 24 hours. When ready to eat, simply bake it as directed.

Can I Freeze Tetrazzini Casserole?

Absolutely. To freeze, assemble the casserole in a freezer-safe dish but do not bake it. Once assembled, cover it tightly with plastic wrap and aluminum foil. It can be stored in the freezer for up to three months. When you're ready to cook it, thaw it in the refrigerator overnight and bake as specified.

Can I Use Different Proteins?

While turkey is the traditional choice, you can easily substitute it with chicken, ham, or even shrimp. Each protein will bring a unique flavor to the dish, allowing for endless variations.

serving of Tetrazzini Casserole on a white plate ready to enjoy

🥘More Easy Casseroles

If you've enjoyed crafting the Tetrazzini Casserole, you're in for a delightful culinary journey with more pasta casserole recipes! These comforting dishes not only provide the warmth and satisfaction we all crave, but they also allow for a world of variations to suit your taste.

  • Baked Ziti Casserole
  • Creamy Mushroom Casserole
  • Spicy Mac and Cheese Casserole
  • Turkey and Pasta Casserole
  • Four Cheese Pasta Casserole

More Best Chicken Casserole Recipes

  • cast iron dish of chicken bake with anchovy cashew
    Chicken Bake with Anchovy Cashews
  • No-Stir Risotto Bake
  • Mum’s Curried Chicken Bake (Tandoori Chicken Curry)
  • serving of chicken divan in a bowl on the table ready to enjoy
    Chicken Divan

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